Computational Biology, Biostatistics & Modeling (CB2M)

The missions of this platform are as follows:

  • Ensuring a professional support in usual (bio)informatic fields to related scientific projects developed at the CIML
  • Offering an appropriate environment (tools and equipment) as well as formation and expertise to CIML scientists (engineer, student, post-doc...) who are willing to develop projects comprised of a theoretical aspect (system biology, modeling, etc...).

Lab. Toby LAWRENCE

A remarkable feature of the innate immune system is its ability to recognize invading microorganisms and to trigger a host defense response. Of particular interest are the recently identified Toll-like receptors (TLRs), which show homology with the Drosophila Toll protein and the interleukin-1 receptor family. The TLRs are transmembrane proteins characterized by the presence of extracellular leucine-rich repeats and an intracellular Toll/interleukin-1 receptor-like domain.