A " self-renewal kit " similar to those carried by embryonic stem cells slumbers in macrophages.

Submitted by admin on Sun, 01/31/2016 - 21:25
By turning off "gene switches" MafB and c-Maf, the Michael SIEWEKE’s team, associating the CIML and the Max Delbrück Center for Moleculare Medicine (MDC) in Berlin, has previously shown that mature immune cells like macrophages were capable of multiplying almost infinitely.

Eric Vivier has been selected for the Thomson Reuters 2015 list of Highly Cited Researchers

Eric VIVIER has been selected to appear on the 2015 edition of the world’s highly cited researcher list. Published every year by Thomson Reuters, a major multinational mass media and information firm,  this list honors the authors of the most cited publications by the scientific community.

Michael Sieweke awarded one of the first Einstein BIH

Michael Sieweke awarded Einstein BIH fellowship by the Berlin Institute of Health. The prestigious German award “Einstein BIH Visiting Fellow” recognizes international top researchers with the aim to foster closer interactions with the research landscape in Berlin and make the fellows’ expertise available to the local scientific community. More informations...

The indefinite self-renewal of specialized cells without the need for stem cell intermediates

The team led by Michael Sieweke at the Centre d'immunologie de Marseille Luminy (Université Aix-Marseille 2 / CNRS / INSERM) has proved that this is the case by achieving the ex vivo regeneration for several months of macrophages, specialized cells in the immune system. Published in Science on November 6, 2009, this discovery could be applied to other cell types. This research enables a clearer understanding of the mechanisms underlying cell differentiation, but above all raises many hopes for potential therapeutic applications. More information...

François Kourilsky, co-founder of the CIML, died on May 31st 2014

François Kourilsky, co-founder of the CIML, died on May 31st 2014
World-class physician and immunologist, his work on tumor biology and the major histocompatibility complex contributed significantly to what many historians of science refer to today as an immunological revolution. François Kourilsky together with Michel Fougereau founded the CIML in 1976; he was general director of the CNRS from 1988 to 1994 (more to come soon online).

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