Testicular macrophages, guardians of fertility

Michael SIEWEKE's team at the Centre d’Immunologie de Marseille-Luminy described the origin, development, and characteristics of two types of testicular macrophage. To elucidate the nature of these immune cells, the researchers used a novel cell tracing method. Their findings were published on August 7, 2017, in the Journal of Experimental Medicine, and are of fundamental importance. They may help understand certain kinds of infertility in men and find new treatments for them.