2019 PhD Calls

1- Alexopoulou Lena "TLR7 at the interface of obesity and metabolic syndrome"
2- Arguello Rafael "Translation regulation during infection and stress"
3- Auphan-Anezin Nathalie "Role of IKKb/NF-kB signaling in the immune surveillance of melanomas"
4- Bajénoff Marc "Macrophage-Stroma crosstalk in lymphoid organs"
5- Gaya Mauro "Deciphering the early events of B cell immunity in the lung mucosa"
6- Hamon Yannick "Unravel the link between TCR, IFN-γR and cholesterol/ABCs pathways in CD4 T cell"
7- Henri Sandrine "Deciphering the Tumor-associated Myeloid Cell Heterogeneity: Toward a Better understanding and better manipulation of XCR1+ cDC1 and tumor-associated macrophages in vivo to improve cancer-immunotherapy and avoid auto-immunity"
8- Irla Magali "Characterizing a novel immune checkpoint controlling the suppressive activity of regulatory T cells"
9- Lelouard Hugues "Rôle du système phagocytaire des plaques de Peyer dans l’initiation de la réponse immunitaire intestinale"
10- Memet Sylvie "Analysis of the signalling induced by Brucella oligosaccharides in the inflammatory response"
11- Payet Dominique "Role of PTEN in thymopoiesis and leukemogenesis"
12- Pujol Nathalie "How are damage responses triggered in the skin?"
13- Roulland Sandrine "Integrative study of B Cell Receptor signaling pathway in B cell lymphoma and therapeutic targeting"
14- Sieweke Michael "De la cellule souche au macrophage : transmission d’une mémoire épigénétique ?"
15- Tomasello Elena "Etude des fonctions physiologiques des cellules dendritiques plasmacytoïdes"
16- Ugolini Sophie "Regulation of the skin immune response by the sensory nervous system"
17- Van de Pavert "Ontogeny of Innate Lymphoid Cells"

See the projects

Nobel 2018: ahead of the work by James Allison, a discovery of Pierre Golstein's team

The Nobel Prize awards in Medicine 2018 are based in part on a discovery made in 1987 in the laboratory of Pierre GOLSTEIN, director of research Inserm. It is indeed his team at the Centre d'Immunologie de Marseille-Luminy  that for the first time identified the CTLA-4 protein, now targeted in certain cancer immunotherapy strategies.

A new member of the immunoglobulin superfamily: CTLA-4. Signed by Pierre Golstein and his team at the Centre d'Immunologie de Marseille-Luminy, this article published on July 16, 1987 in the journal Nature has been cited several hundred times in the scientific literature. This publication is also the origin of the works of James Allison rewarded this year by the Nobel Academy.

A new member of the immunoglobulin superfamily-CTLA-4,
Jean-François Brunet, François Denizot, Marie-Françoise Luciani, Magali Roux-Dosseto, Marie Suzan, Marie-Geneviève Mattei & Pierre Golstein. Nature, volume 328, pages 267–270, 1987