250 ! HAPPY BIRTHDAY, ALEXANDER VON HUMBOLDT!
On September 14, 1769, Alexander von Humboldt was born – just 250 years ago.
On the occasion, the Sieweke lab held a dedicated lab retreat at CIML. Humboldt-Professor and CIML group leader Michael Sieweke reflects on the great discoverer and pioneer of Franco-German research cooperation.
The research teams of Michael SIEWEKE, French and German, meet for a retreat at the CIML on October 14, 2019. Copyright: Michael Sieweke / Michaela Burkon
Scientists find potential ‘magic bullet’ for treating tumours
Researchers from the Centre d'Immunologie de Marseille-Luminy (CIML), Inserm, CNRS et Aix-Marseille Université in France and King’s College London have found a therapy to reduce the size of tumours where previous drugs have failed
Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression
Etzerodt A, Tsalkitzi K, Maniecki M, Damsky W, Delfini M, Baudoin E, Moulin M, Bosenberg M, Graversen JH, Auphan-Anezin N, Moestrup SK, Lawrence T. J Exp Med, 2019, pii: jem.20182124, PMID: 31375534
2019 PhD Calls
1- Alexopoulou Lena "TLR7 at the interface of obesity and metabolic syndrome"
2- Arguello Rafael & Ewbank Jonathan "Translation regulation during infection and stress"
3- Auphan-Anezin Nathalie "Role of IKKb/NF-kB signaling in the immune surveillance of melanomas"
4- Bajénoff Marc "Macrophage-Stroma crosstalk in lymphoid organs"
5- Gaya Mauro "Deciphering the early events of B cell immunity in the lung mucosa"
6- Hamon Yannick & He Hai-Tao "Unravel the link between TCR, IFN-γR and cholesterol/ABCs pathways in CD4 T cell"
7- Henri Sandrine "Deciphering the Tumor-associated Myeloid Cell Heterogeneity: Toward a Better understanding and better manipulation of XCR1+ cDC1 and tumor-associated macrophages in vivo to improve cancer-immunotherapy and avoid auto-immunity"
8- Irla Magali "Characterizing a novel immune checkpoint controlling the suppressive activity of regulatory T cells"
9- Lelouard Hugues "Rôle du système phagocytaire des plaques de Peyer dans l’initiation de la réponse immunitaire intestinale"
10- Memet Sylvie "Analysis of the signalling induced by Brucella oligosaccharides in the inflammatory response"
11- Payet Dominique "Role of PTEN in thymopoiesis and leukemogenesis"
12- Pujol Nathalie "How are damage responses triggered in the skin?"
13- Roulland Sandrine "Integrative study of B Cell Receptor signaling pathway in B cell lymphoma and therapeutic targeting"
14- Sieweke Michael "De la cellule souche au macrophage : transmission d’une mémoire épigénétique ?"
15- Tomasello Elena "Etude des fonctions physiologiques des cellules dendritiques plasmacytoïdes"
16- Ugolini Sophie "Regulation of the skin immune response by the sensory nervous system"
17- Van de Pavert "Ontogeny of Innate Lymphoid Cells"
At the crossroads of biology and medicine, immunology is a scientific discipline that focuses on the operating mechanisms of the immune system. Appeared early in the evolution, this system enables living organisms to defend themselves against pathogens or their own components when they are altered. It involves a large number of cells whose capacity for cooperation, recognition and memory are far from having revealed all their secrets.
ERC "Advanced Grants"
Bernard Malissen – 2018 – Basilic Projet
Michael Sieweke – 2016 – Macrophage Aging and Rejuvenation
Eric Vivier – 2016 – Targeting Innate Lymphoid Cells
Bernard Malissen – 2012 – Integrative biology of T cells and dendritic cells in vivo
Eric Vivier – 2010 – The Immune Function of Natural Killer
ERC "Consolidator Grants"
Sophie Ugolini – 2014 – Neural regulation of immunity
Marc Bajénoff – 2014 – Immunobiology of lymphoid stromal cells
ERC "Starting Grants"
Marc Dalod – 2011 – Harnessing systems immunology to unravel dendritic cell subset biology
Toby Lawrence - 2010 – Targeting tumor associated macrophages in Cancer
ERC "Proof of Concept (PoC) Grant"
Eric Vivier - 2019 - MInfla-Tilc
Discover our close-ups and our video archives.