Events

Wonhwa CHO, University of Illinois, Chicago, USA
"Quantitative In Situ Imaging of Cellular Lipid Dynamics"
Host: Yannick HAMON

Ralf ADAMS, Max Planck Institut, Muenster, D
Host: Serge VAN DE PAVERT

Robert NIBBS, University of Glasgow, UK
Host: Serge VAN DE PAVERT

News

The work of Rafael José ARGUELLO, CNRS researcher in Philippe PIERRE's team at the Centre d'Immunologie de Marseille-Luminy (CIML),…

The Nobel Prize awards in Medicine 2018 are based in part on a discovery made in 1987 in the laboratory of Pierre GOLSTEIN, director of research Inserm. It is indeed his team at…

The team of Sophie UGOLINI, Research Director at Inserm and team leader at the Centre d'Immunologie de Marseille-Luminy, Inserm, CNRS and Aix-Marseille University describes new…

Nobel 2018: ahead of the work by James Allison, a discovery of Pierre Golstein's team

 

Pierre Gols

The Nobel Prize awards in Medicine 2018 are based in part on a discovery made in 1987 in the laboratory of Pierre GOLSTEIN, director of research Inserm. It is indeed his team at the Centre d'Immunologie de Marseille-Luminy  that for the first time identified the CTLA-4 protein, now targeted in certain cancer immunotherapy strategies.

A new member of the immunoglobulin superfamily: CTLA-4. Signed by Pierre Golstein and his team at the Centre d'Immunologie de Marseille-Luminy, this article published on July 16, 1987 in the journal Nature has been cited several hundred times in the scientific literature. This publication is also the origin of the works of James Allison rewarded this year by the Nobel Academy.

A new member of the immunoglobulin superfamily-CTLA-4,
Jean-François Brunet, François Denizot, Marie-Françoise Luciani, Magali Roux-Dosseto, Marie Suzan, Marie-Geneviève Mattei & Pierre Golstein. Nature, volume 328, pages 267–270, 1987

What is Immunology

At the crossroads of biology and medicine, immunology is a scientific discipline that focuses on the operating mechanisms of the immune system. Appeared early in the evolution, this system enables living organisms to defend themselves against pathogens or their own components when they are altered. It involves a large number of cells whose capacity for cooperation, recognition and memory are far from having revealed all their secrets.

Publications

Chiossone L. et al., Nature Reviews Immunology,
Vivier E. et al., Cell, , 174(5):1054-1066
Tomasello E. et al., EMBO J., , pii: e98836., PMID: 30131424
Golstein P. et al., Nat Rev Immunol., , PMID: 29662120

Vidéos

Discover our close-ups and our video archives.

Enseignement

Thomson Reuters list of highly cited researchers

Pr Eric VIVIER and Dr Bernard MALISSEN have been selected for the Thomson Reuters 2016 and 2017 lists of Highly Cited Researchers

Marseille Immunopole

The french immunology cluster.