Publications

Regulatory T Cell Heterogeneity in the Thymus: Impact on Their Functional Activities

Santamaria JC, Borelli A, Irla M. Front Immunol, 2021 , 12, PMID: 33643324

RANK Signaling in the Differentiation and Regeneration of Thymic Epithelial Cells.

Irla M. Front Immunol., 2021 , 11, PMID: 33552088

Intrathymic adeno-associated virus gene transfer rapidly restores thymic function and long-term persistence of gene-corrected T cells

Pouzolles M, Machado A, Guilbaud M, Irla M, Gailhac S, Barennes P, Cesana D, Calabria A, Benedicenti F, Sergé A, Raman I, Li QZ, Montini E, Klatzmann D, Adjali O, Taylor N, Zimmermann VS. J Allergy Clin Immunol, 2020 , 145, 679-+, PMID: 31513879

Transforming Growth Factor-beta signaling in αβ thymocytes promotes negative selection

McCarron MJ, Irla M, Sergé A, Soudja SM, Marie JC. Nat Commun., 2019 , 10(1):5690., PMID: 31857584

Lupus Autoimmunity and Metabolic Parameters Are Exacerbated Upon High Fat Diet-Induced Obesity Due to TLR7 Signaling

Hanna Kazazian N, Wang Y, Roussel-Queval A, Marcadet L, Chasson L, Laprie C, Desnues B, Charaix J, Irla M, Alexopoulou L. Front Immunol. , 2019 , 10:2015, PMID: 31552019

Thymic Crosstalk: An Overview of the Complex Cellular Interactions That Control the Establishment of T-Cell Tolerance

Irla M. Springer Nature, 2019 , Book entitled: Thymus Transcriptome and Cell Biology. , 149-167

Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells

Lopes N, Charaix J, Cédile O, Sergé A, Irla M.Nat Commun., 2018 , 9(1):1262, PMID: 29593265

Administration of RANKL boosts thymic regeneration upon bone marrow transplantation

Lopes N, Vachon H, Marie J, Irla M.EMBO Mol Med., 2017 , 9(6):835-851, PMID: 28455312

IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity

Lippens C, Duraes FV, Dubrot J, Brighouse D, Lacroix M, Irla M, Aubry-Lachainaye JP, Reith W, Mandl JN, Hugues S.J Autoimmun., 2016 , (16)30112-3, PMID: 27470005

Induction of central tolerance by the factor Aire: molecular and epigenetic regulation

Lopes N, Ferrier P, Irla M.Med Sci (Paris), 2015 , 31(8-9):742-7, PMID: 26340833