Publications

CD8+ T cells variably recognize native versus citrullinated GRP78 epitopes in type 1 diabetes

Azoury ME, Samassa F, Buitinga M, Nigi L, Brusco N, Callebaut A, Giraud M, Irla M, Lalanne AI, Carré A, Afonso G, Zhou Z, Brandao B, Colli ML, Sebastiani G, Dotta F, Nakayama M, Eizirik DL, You S, Pinto S, Mamula MJ, Verdier Y, Vinh J, Buus S, Mathieu C, Overbergh L, Mallone R Diabetes, 2021 , 70, 2879-2891, PMID: 34561224

Receptor repertoires of murine follicular T helper cells reveal a high clonal overlap in separate lymph nodes in autoimmunity

Niebuhr M, Belde J, Fähnrich A, Serge A, Irla M, Ellebrecht CT, Hammers CM, Bieber K, Westermann J, Kalies K. Elife, 2021 , PMID: 34402793

Lymphotoxin: from the physiology to the regeneration of the thymic function

Borelli A, Irla M. Cell Death Differ
, 2021 , PMID: 34290396

Regulatory T Cell Heterogeneity in the Thymus: Impact on Their Functional Activities

Santamaria JC, Borelli A, Irla M. Front Immunol, 2021 , 12, PMID: 33643324

RANK Signaling in the Differentiation and Regeneration of Thymic Epithelial Cells.

Irla M. Front Immunol., 2021 , 11, PMID: 33552088

Intrathymic adeno-associated virus gene transfer rapidly restores thymic function and long-term persistence of gene-corrected T cells

Pouzolles M, Machado A, Guilbaud M, Irla M, Gailhac S, Barennes P, Cesana D, Calabria A, Benedicenti F, Sergé A, Raman I, Li QZ, Montini E, Klatzmann D, Adjali O, Taylor N, Zimmermann VS. J Allergy Clin Immunol, 2020 , 145, 679-+, PMID: 31513879

Transforming Growth Factor-beta signaling in αβ thymocytes promotes negative selection

McCarron MJ, Irla M, Sergé A, Soudja SM, Marie JC. Nat Commun., 2019 , 10(1):5690., PMID: 31857584

Lupus Autoimmunity and Metabolic Parameters Are Exacerbated Upon High Fat Diet-Induced Obesity Due to TLR7 Signaling

Hanna Kazazian N, Wang Y, Roussel-Queval A, Marcadet L, Chasson L, Laprie C, Desnues B, Charaix J, Irla M, Alexopoulou L. Front Immunol. , 2019 , 10:2015, PMID: 31552019

Thymic Crosstalk: An Overview of the Complex Cellular Interactions That Control the Establishment of T-Cell Tolerance

Irla M. Springer Nature, 2019 , Book entitled: Thymus Transcriptome and Cell Biology. , 149-167

Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells

Lopes N, Charaix J, Cédile O, Sergé A, Irla M.Nat Commun., 2018 , 9(1):1262, PMID: 29593265