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  3. Lab. Lena ALEXOPOULOU
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Arthritogenic properties of double-stranded (viral) RNA
Zare, F.J Immunol, 2004 , 172, 5656-63, PMID: 15100310
Recognition of single-stranded RNA viruses by Toll-like receptor 7
Lund, J. M.Proc Natl Acad Sci U S A, 2004 , 101, 5598-603, PMID: 15034168
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
Tabeta, K.Proc Natl Acad Sci U S A, 2004 , 101, 3516-21, PMID: 14993594
Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways
Hoebe, K.Nat Immunol, 2003 , 4, 1223-9, PMID: 14625548
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice
Alexopoulou, L.Nat Med, 2002 , 8, 878-84, PMID: 12091878
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
Alexopoulou, L.Nature, 2001 , 413, 732-8, PMID: 11607032

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Team leader
Lena ALEXOPOULOU, DR2, PhD

See biography...

Selected publications

The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling
Desnues B., Eur J Immunol., 2016 , PMID: 27600904
TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL/6 mice.
Desnues B., Proc Natl Acad Sci USA, 2014 , 1497-502, PMID: 24474776
Sex Bias in Susceptibility to MCMV Infection: Implication of TLR9
Traub S., PLoS One, 2012 , 45171, PMID: 23028824
TLR8 deficiency leads to autoimmunity in mice
Demaria, O., J Clin Invest, 2010 , 3651-62, PMID: 20811154
Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria
Feuillet, V., Proc Natl Acad Sci U S A, 2006 , 12487-92, PMID: 16891416
Recognition of single-stranded RNA viruses by Toll-like receptor 7
Lund, J. M., Proc Natl Acad Sci U S A, 2004 , 5598-603, PMID: 15034168
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
Alexopoulou, L., Nature, 2001 , 732-8, PMID: 11607032

Contact

Lena ALEXOPOULOU
Tel: +33 (0)4 91 26 94 59

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