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Wed, 09/12/2018 - 12:00

CNRS Actualités

Comment produire au laboratoire les cellules dendritiques les plus efficaces contre le cancer?
Les cellules dendritiques,…

Wed, 08/15/2018 - 12:00

ResearchGate

Immune cell type best suited for cancer vaccines can now be grown in the lab
New approach paves the way to making dendritic…

Tue, 08/14/2018 - 12:00

Mount Sinai

Researchers Artificially Generate Immune Cells Integral To Creating Cancer Vaccines
…

Tue, 08/14/2018 - 12:00

Balan S. et al., Cell Reports, 2018

The team of Marc DALOD, CNRS Team Leader at the Centre d'Immunologie de Marseille-Luminy, CNRS, Inserm and Aix-Marseille…

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Team leader

Marc DALOD, DR1, PhD

See biography...

The team

Ramazan
AKYOL - PhD Student

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AKYOL Ramazan

PhD Student, AMU

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Gilles
BESSOU - IEHC

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BESSOU Gilles

IEHC, INSERM

Gilles Bessou joined the team at its vey beginning in 2004 as a tenure engineer from Inserm. He is managing the laboratory and many of the mouse colonies used by the team. He contributes to transferring or developing novel experimental protocols in the team. He also is the Hygiene and Security officer for the CIML Institute with regards to biohazard, especially for everything linked to the operating of level 2 or 3 laboratories.

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Clémence
GARREC - PhD Student

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GARREC Clémence

PhD Student, CNRS

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Abel
LOPEZ HERNANDEZ - PhD student

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LOPEZ HERNANDEZ Abel

PhD student, CNRS

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Clémence
NGO - PhD Student

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NGO Clémence

PhD Student, AMU

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Khalissa
RAHMANI - IE

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RAHMANI Khalissa

IE, AMIDEX

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Elena
TOMASELLO - CRCN

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TOMASELLO Elena

CRCN, CNRS

Elena Tomasello, PhD, CR1 CNRS, Italian Senior Researcher, joined the team in 2012.
Her main research interest is the dissection of the molecular mechanisms regulating the functional heterogeneity of mouse and human plasmacytoid dendritic cells.

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Melissa
TOXE - IE

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TOXE Melissa

IE, CNRS

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Thien phong
VU MANH - CRCN

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VU MANH Thien phong

CRCN, CNRS

After a 2-year postdoctoral experience at the Centre for Genomic Regulation (CRG, Barcelona, Spain), Thien-Phong joined the CIML in 2010 as a post-doc fellow. He is now a CNRS researcher and is interested in deciphering, using bulk and single cell genomics approaches, the cell-intrinsic and -extrinsic regulation that occurs in dendritic cells and more generally mononuclear phagocytes, how this instructs cell differentiation/activation, and how the interplay between different types and activation states of mononuclear phagocytes manages and fine tunes the immune response.

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Selected publications

Natural killer cells and dendritic epidermal γδ T cells orchestrate type 1 conventional DC spatiotemporal repositioning toward CD8 + T cells
Ghilas S., iScience, 2021 , 9

Type 1 conventional dendritic cells and interferons are required for spontaneous CD4+ and CD8+ T-cell protective responses to breast cancer
Mattiuz R., Clin Transl Immunology, 2021 , PMID: 34277006

The activation trajectory of plasmacytoid dendritic cells in vivo during a viral infection
Abbas A, Nat Immunol., 2020 , PMID: 32690951

Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery
Ardouin L., Immunity, 2016 , PMID: 27533013

XCR1+ dendritic cells promote memory CD8+ T cell recall upon secondary infections with Listeria monocytogenes or certain viruses
Alexandre YO., J Exp Med., 2016 , PMID: 26694969

Natural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse Cytomegalovirus
Cocita C., PLoS Pathog., 2015 , PMID: 25954804

Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells
Balan S., J Immunol., 2014 , 1622-35, PMID: 25009205

Differential responses of immune cells to type I interferon contribute to host resistance to viral infection
Baranek T., Cell Host Microbe, 2012 , 571-584, PMID: 23084923

Cutting Edge: Expression of XCR1 Defines Mouse Lymphoid-Tissue Resident and Migratory Dendritic Cells of the CD8{alpha}+ Type
Crozat K., J Immunol, 2011 , PMID: 21948982

Contact

Marc DALOD

Tel: +33 (0)4 91 26 94 51

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